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AGE CONFIDENCE

Age Confidence™ NAD+ & TriPeptide Renewal Serum

Name: Age Confidence™ NAD+ & TriPeptide Renewal Serum
Brand: Pai Skincare
SKU: PAI-2022
Price: 119.00 USD
Availability: InStock

$119.00

30ml / 1.0 fl.oz

A cell renewal serum that addresses the root cause of aging, not just what shows on the surface. In four weeks, it's clinically proven to significantly firm skin and reduce wrinkle depth.

Clinically Proven:

Instantly revitalise and reduce wrinkle depth in just 4 weeks*
10% reduction in wrinkle depth, 11% increase in firmness, 17% increase in hydration by 8 weeks**
73% saw instantly smoother, more revitalised skin after one use*

Learn more

Benefits:

Firms skin
Smooths wrinkles
Rejuvenates
Patch tested

Free delivery when you spend $49

Easy 90-Day returns

GUIDE TO LAYERING:

Step 1: Eye Cream

Pai Skincare Eye Cream Feather Canyon Echium & Argan Eye Cream

Feather Canyon™ Smoothing Eye Cream

$64.00

/ 15ml / 0.5 fl.oz

Step 2: Serum

Age Confidence™ NAD+ & TriPeptide Renewal Serum

$119.00

/ 30ml / 1.0 fl.oz

Step 3: Moisturiser

Age Confidence™ PDRN Revival Moisturizer

$109.00

/ 50ml / 1.7 fl.oz

Add full routine - save 10%

Age Confidence™ NAD+ & TriPeptide Renewal Serum

$119.00

Proven Results

Clinically Proven

Instantly revitalise and reduce wrinkle depth in just 4 weeks*

10% reduction in wrinkle depth, 11% increase in firmness, 17% increase in hydration by 8 weeks**

73% saw instantly smoother, more revitalised skin after one use*

Visibly lifted skin**

Why You'll Love It

Kick your skin into age-defying action.
Think of it as a biohack for your complexion. This longevity serum combines NAD+ science with collagen-boosting peptide technology, clinically proven to revitalize on contact and significantly reduce wrinkle depth in four weeks*. Cue ultra-plump, smoother skin that's visibly bouncier.

Where most serums chase visible signs of aging one at a time, this one goes after the underlying driver: a decline in cellular energy that fuels every change you see. Our fragrance-free clear gel is built to recharge skin at the cellular level, effectively rewinding its clock. An advanced formula that slows and reverses the signs of aging, without setting off irritation.

Here's the breakdown. Sunflower Sprout Extract switches on your skin's own NAD+ production, re-energizing cells to fire on all cylinders. A biofermented TriPeptide Complex eases expression lines, evens out tone, and takes on puffiness and dark circles. Exosome-rich Centella Asiatica acts like a messenger, sending repair signals straight to skin cells. Broad spectrum Hyaluronic Acid, including an enzyme-resistant form for longer-lasting moisture, hydrates at every depth. Fine lines look softened, firmness lifts, and skin renews from the cellular floor up.

*Based on a clinical study of 21 subjects over 8 weeks and an independent consumer trial of 100 subjects (Eurofins Alba, 2025).

“Over time our skin’s natural regenerative processes slow down. This NAD+ boosting elixir provides an energy surge for every single skin cell – powering their natural processes. Fully functioning skin cells mean a firmer, smoother complexion that radiates health. An instant lift for well-lived skin.”

SARAH BROWN
FOUNDER, PAI SKINCARE

What is NAD+?

NAD+ occurs naturally in our body and acts as a battery for our skin cells. It powers vital processes including detoxification, DNA protection and barrier support, to name just a few. As we age, our NAD+ production declines, meaning our skin cells lose their power and slow down – leading to signs of ageing. NAD+ can’t be applied topically, but we’ve used a Sunflower Sprout Extract which stimulates NAD+ production to recharge your skin at a cellular level.

How should I use the NAD+ Renewal Serum in my routine?

Apply one pump to cleansed, dry skin morning and night, avoiding the eye area. The clear gel absorbs quickly and layers well under moisturisers, oils, and SPF. For a complete Age Confidence routine, follow with Salvation Jane in the morning or Bonne Nuit at night, and pair with Feather Canyon Eye Cream for the eye area.

Is this serum suitable for sensitive skin?

Yes. It's been clinically proven for sensitive skin through a 96-hour human repeat insult patch test, and a 100-person consumer trial recorded only 2 mild adverse events, both of which resolved. The formula is fragrance-free, essential oil-free, alcohol-free, and non-comedogenic.

Is this serum safe to use during pregnancy and breastfeeding?

Yes. The formula is certified pregnancy and breastfeeding safe, made with 100% natural-origin ingredients and free from retinoids, fragrance, essential oils, and alcohol. It's been independently patch tested through a 96-hour human repeat insult protocol, so you can use it with confidence throughout pregnancy and while nursing.

Can I use this serum with retinol or vitamin C?

Yes. The formula contains no ingredients that conflict with retinol or vitamin C, so you can layer it alongside either. Apply the serum first to cleansed skin, let it absorb, then follow with your retinol or vitamin C product. If you're using retinol, it's best kept to your evening routine, while this serum works well both morning and night.

What results can I expect and how quickly?

In an independent 100-person consumer trial, 73% agreed skin felt revitalised and looked smoother immediately after first use. Over time, results build: a 21-subject clinical study measured a 9.45% reduction in wrinkle depth, 11% improvement in firmness, and 17.95% improvement in hydration by eight weeks, with statistically significant firming and wrinkle reduction from just four weeks.

What are the three peptides in this serum and what do they do?

The TriPeptide Complex combines three biofermented peptides. Acetyl Hexapeptide-8 modulates the micro-contractions that deepen expression lines, with a placebo-controlled study of 60 subjects showing 48.9% anti-wrinkle efficacy versus 0% for placebo. Glutathione inhibits tyrosinase to help even skin tone by shifting melanin production towards lighter pigment, while Acetyl Tetrapeptide-5 promotes microcirculation to reduce the appearance of puffiness and dark circles.

How does the hyaluronic acid in this serum differ from standard HA?

It includes a broad spectrum of molecular weights, from high (which forms a moisture-retaining film on the surface) to low (which penetrates deeper into the epidermis for hydration from within). The formula also contains sodium acetylated hyaluronate, a modified HA that's chemically protected against breakdown by hyaluronidase, the enzyme that rapidly degrades standard HA on skin, so moisture lasts longer.

What is exosome-rich Centella Asiatica and why is it in this serum?

Centella Asiatica is a well-established regenerative botanical, but this extract is notable for its concentration of plant-derived exosomes. These are nano-sized vesicles (30–150nm) that act as biological messengers, delivering peptides and plant growth factors directly to skin cells rather than just sitting on the surface. Peer-reviewed research confirms that Centella-derived exosomes promote barrier recovery, collagen synthesis, and fibroblast proliferation (Chang et al., IJMS, 2025), and a separate study found exosome-treated skin cells showed substantially more gene expression activity than those treated with standard extracts (Cho et al., 2022).

What does the prebiotic Inulin do in this formula?

Inulin is a chicory root-derived prebiotic that selectively feeds the beneficial bacteria on your skin while inhibiting pathogens. This supports a balanced skin microbiome, which strengthens barrier function and helps reduce irritation. Think of it as the support crew keeping your skin's ecosystem stable while the other actives do their work.

What certifications does this serum hold?

It's COSMOS Natural certified by the Soil Association, Vegan, and Cruelty-Free (Leaping Bunny approved). The formula is also free from parabens, silicones, sulfates, mineral oil, PEGs, SLS, phthalates, palm oil, GMOs, and 18+ additional exclusions. Pai itself is a certified B Corp, so those standards extend beyond the formula to how the business operates.

What makes this serum different from other anti-ageing serums?

Most anti-ageing serums treat wrinkles, dullness, and dryness as separate symptoms. This one targets the cellular energy decline that drives them all, restoring the NAD+ supply that powers your skin's own repair and renewal processes from within.

It's also one of the few serums to combine biofermented peptides, exosome-rich Centella Asiatica, and enzyme-resistant hyaluronic acid in a fully COSMOS Natural certified formula. That level of biotech complexity in a certified natural product is genuinely unusual.

Who is this serum best suited for?

It's designed for anyone noticing that their skin's natural repair processes are slowing down, typically from your mid-thirties onwards, when NAD+ levels begin to decline significantly. All skin types can use it, including sensitive, oily, and combination skin. The clear gel formula is non-comedogenic and fragrance-free. If your main concerns are fine lines, loss of firmness, dullness, or dehydration, this is a strong starting point.

Overall rating: 4.836364 / 5 from 55 reviews.

AI Generated Review Summary

Age Confidence™ NAD+ & TriPeptide Renewal Serum revitalizes skin by reducing wrinkle depth and enhancing elasticity. Customers report smoother, firmer, and healthier-looking skin with regular use.

Summary topics

Skin Feel (35%): A substantial number of customers remarked that this product feels great and leaves their skin feeling smoother and more moisturized.
Skin Appearance (60%): Many customers pointed out that the product made their skin look fresher, firmer, and healthier.

Review topics: ["feels","improvement","results","serum","looks","texture","skin","lines","irritation","difference","buy","effect","use","cruelty","works"].

Review highlights

"My skin feels smoother and more moisturised." — Lesley F.
"My skin feels fuller, brighter, improved elasticity and tighter (in the best way!)" — Zoe G.
"Skin is fresh and firm" — Pauline P.

Reviews

Amazing

"Used for about 3 weeks and it’s amazing so far. My skin looks and feels a million miles better. Only need one pump morning and night will definitely repurchase."

— Andrew (5/5)

My new favourite

"I have been a ‘Pai patron’ for many years now and me and my skin absolutely love their products. This serum is so good! My skin drinks it in. I have definitely seen an improvement in fine lines and the luminosity of my skin."

— Angie B. (5/5)

Best skin care ever!

"Beautiful products from PAI, All cruelty free and organic , vegan and with ‘no nasties’ My skin is the proof! That these products are pure and kind to my skin! Thankyou Pai."

— Barbara B. (5/5)

Favourites

"This serum has to be one of my favourites. Im on my first bottle and a couple of weeks in and I can already see the difference."

— Jill T. (5/5)

Effective serum

"After a couple of weeks of using this serum fine lines were definitely improving and skin appeared more toned. Applies easily and absorbs well. My only issue was it left my skin slightly dry, but it was during Autumn/Winter, so I started using my go to serum Back To Life in the evenings again which quickly fixed the problem. I’d definitely consider trying it again, but maybe not during Autumn/Winter."

— Mike C. (4/5)

Renewal Serum

"I use this serum every day and find it a great addition to my routine."

— Rose B. (5/5)

A wonderful product

"I Have been using this product for a while, and I can say that my skin looks healthier, more hydrated and plumber. The serum is very light, doesn’t cause any irritation and leaves my skin feeling great. Thank you, Pai."

— SONIA A. (5/5)

Espectacular

"Esto es verdaderamente un producto que ha cambiado espectacularmente mi piel. Estoy increíblemente sorprendida sobre sus efectos sobre las arrugas y la sensación de relleno que aporta. Me encanta, he usado siempre los mejores productos, incluso cremas de Biologique Recherche y esto no tiene parangón, incluso siendo una fiel consumidora de BR. En cuanto a textura es verdad que es pegajosa, pero si dejas que se absorba totalmente antes de la crema esto desparece. Solo hay que esperar un poco antes de la siguiente capa. Y si fuera pegajosa luego de su absorción creo que no me importaría teniendo en cuenta los resultados."

— Mariana M. (5/5)

Age confidence renewal serum

"This product is so Beautiful. Feel Like silk on my skin."

— Laura K. (5/5)

Eureka

"Have been using this about 5 months now and will continue to use it forever. This is wonderful, kind to sensitive skin and helps hugely with dryness and declining elasticity."

— Micky F. (5/5)

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