My new favourite
"I have been a ‘Pai patron’ for many years now and me and my skin absolutely love their products. This serum is so good! My skin drinks it in. I have definitely seen an improvement in fine lines and the luminosity of my skin."
Age Confidenceā¢ NAD+ & TriPeptide Renewal Serum
Regular price
$119.00
Unit price
per
30ml / 1.0 fl.oz
A cell renewal serum that addresses the root cause of aging, not just what shows on the surface. In four weeks, it's clinically proven to significantly firm skin and reduce wrinkle depth.
Smooths fine lines & wrinkles
Plumping
Collagen boosting
Regenerating
Free delivery when you spend $49 (Mainland USA) | 90-Day returns
Why You'll Love It
Kick your skin into age-defying action.
Think of it as a biohack for your complexion. This longevity serum combines NAD+ science with collagen-boosting peptide technology, clinically proven to revitalize on contact and significantly reduce wrinkle depth in four weeks*. Cue ultra-plump, smoother skin that's visibly bouncier.
Where most serums chase visible signs of aging one at a time, this one goes after the underlying driver: a decline in cellular energy that fuels every change you see. Our fragrance-free clear gel is built to recharge skin at the cellular level, effectively rewinding its clock. An advanced formula that slows and reverses the signs of aging, without setting off irritation.
Here's the breakdown. Sunflower Sprout Extract switches on your skin's own NAD+ production, re-energizing cells to fire on all cylinders. A biofermented TriPeptide Complex eases expression lines, evens out tone, and takes on puffiness and dark circles. Exosome-rich Centella Asiatica acts like a messenger, sending repair signals straight to skin cells. Broad spectrum Hyaluronic Acid, including an enzyme-resistant form for longer-lasting moisture, hydrates at every depth. Fine lines look softened, firmness lifts, and skin renews from the cellular floor up.
*Based on a clinical study of 21 subjects over 8 weeks and an independent consumer trial of 100 subjects (Eurofins Alba, 2025).
Directions
Full Ingredients
Recycling
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Clinically proven
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100%
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Instantly
Key Ingredients
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Sunflower Sprout Extract
This biotech active acts like a battery for your skin by boosting NAD+ production, which declines as you age. NAD+ energisesĀ every skin cell to power its processes ā including detoxification, DNA protection and barrier support. Fully charged skin means a fresher, smoother, rejuvenated complexion that radiates health.
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Tripeptide Complex
Why have one collagen-boosting peptide when you can have three? This 100% natural biotech complex plumps, firms and smooths. Acetyl Hexapeptide-8 blocks nerve signals to reduce the appearance of fine lines, antioxidant Glutathione helps inhibit melanin production to improve skin tone ā and Acetyl Tetrapeptide-5 promotes microcirculation to improve the appearance of puffiness and dark circles.
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Centella Asiatica
This hardworking herb is packed with protective antioxidants and exosomes that are bursting with peptides and plant growth factors ā AKA communicators that tell your skin to regenerate. Giving it the fuel it needs to stimulate collagen, boost elasticity and support the barrier for firmer, stronger, smoother skin.
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Broad Spectrum Hyaluronic Acid
This hero humectant is a must for hydration. But our chemists pushed it to the next level by including a broad spectrum of low to high molecular weight ā giving superior skin penetration for maximum moisture.
āOver time our skinās natural regenerative processes slow down. This NAD+ boosting elixir provides an energy surge for every single skin cell ā powering their natural processes. Fully functioning skin cells mean a firmer, smoother complexion that radiates health. An instant lift for well-lived skin.ā
SARAH BROWN
FOUNDER, PAI SKINCARE
Frequently Asked Questions
What is NAD+?
How should I use the NAD+ Renewal Serum in my routine?
Is this serum suitable for sensitive skin?
Is this serum safe to use during pregnancy and breastfeeding?
Can I use this serum with retinol or vitamin C?
What results can I expect and how quickly?
What are the three peptides in this serum and what do they do?
How does the hyaluronic acid in this serum differ from standard HA?
What is exosome-rich Centella Asiatica and why is it in this serum?
What does the prebiotic Inulin do in this formula?
What certifications does this serum hold?
What makes this serum different from other anti-ageing serums?
Who is this serum best suited for?
Overall rating: 4.8333335 / 5 from 54 reviews.
AI Generated Review Summary
Age Confidence™ NAD+ & TriPeptide Renewal Serum revitalizes skin by reducing wrinkle depth and enhancing elasticity. Customers report smoother, firmer, and healthier-looking skin with regular use.
Summary topics
- Skin Feel (35%): A substantial number of customers remarked that this product feels great and leaves their skin feeling smoother and more moisturized.
- Skin Appearance (60%): Many customers pointed out that the product made their skin look fresher, firmer, and healthier.
Review topics: ["results","feels","texture","works","skin","looks","irritation","lines","improvement","difference","effect","serum","buy","use"].
Review highlights
- "My skin feels smoother and more moisturised." —
- "My skin feels fuller, brighter, improved elasticity and tighter (in the best way!)" —
- "Skin is fresh and firm" —
Reviews
Best skin care ever!
"Beautiful products from PAI, All cruelty free and organic , vegan and with ‘no nasties’ My skin is the proof! That these products are pure and kind to my skin! Thankyou Pai."
Favourites
"This serum has to be one of my favourites. Im on my first bottle and a couple of weeks in and I can already see the difference."
Effective serum
"After a couple of weeks of using this serum fine lines were definitely improving and skin appeared more toned. Applies easily and absorbs well. My only issue was it left my skin slightly dry, but it was during Autumn/Winter, so I started using my go to serum Back To Life in the evenings again which quickly fixed the problem. I’d definitely consider trying it again, but maybe not during Autumn/Winter."
Renewal Serum
"I use this serum every day and find it a great addition to my routine."
A wonderful product
"I Have been using this product for a while, and I can say that my skin looks healthier, more hydrated and plumber. The serum is very light, doesn’t cause any irritation and leaves my skin feeling great. Thank you, Pai."
Espectacular
"Esto es verdaderamente un producto que ha cambiado espectacularmente mi piel. Estoy increíblemente sorprendida sobre sus efectos sobre las arrugas y la sensación de relleno que aporta. Me encanta, he usado siempre los mejores productos, incluso cremas de Biologique Recherche y esto no tiene parangón, incluso siendo una fiel consumidora de BR. En cuanto a textura es verdad que es pegajosa, pero si dejas que se absorba totalmente antes de la crema esto desparece. Solo hay que esperar un poco antes de la siguiente capa. Y si fuera pegajosa luego de su absorción creo que no me importaría teniendo en cuenta los resultados."
Age confidence renewal serum
"This product is so Beautiful. Feel Like silk on my skin."
Eureka
"Have been using this about 5 months now and will continue to use it forever. This is wonderful, kind to sensitive skin and helps hugely with dryness and declining elasticity."
Velvety smooth
"This is another gem from Pai skincare! The texture is velvety smooth and every evening I am looking forward to working it slowly into my skin. After several applications the results show- my skin looks somehow smoother and so nourished. I even think some fine lines have disappeared! And yes, I just ordered it again!"